References

Andriessen A, Strohal R. Understanding the role of PHMB: a topical approach to wound infection. Wounds International. 2010; 1:(3)25-28

Bellingeri A, Falciani F, Traspedini P Effect of a wound cleansing solution on wound bed preparation and inflammation in chronic Wounds: a single-blind RCT. J Wound Care. 2016; 25:(3)160-8 https://doi.org/10.12968/jowc.2016.25.3.160

Barrett S. Wound bed preparation: a vital step in the healing process. Br J Nurs. 2017; 26:S24-S31 https://doi.org/10.12968/bjon.2017.26.12.S24

Brown A. Diagnosing and managing infection in acute and chronic wounds. Nursing Times. 2018; 114:(7)36-41

Brown A. Antibiotic prescribing in wound care. Nurse Prescribing. 2015; 13:(9)380-5 https://doi.org/10.12968/npre.2015.13.9.446

Cooper R A, Bjarnsholt T, Alhede M. Biofilms in wounds: a review of present knowledge. J Wound Care. 2014; 23:(11)570-80 https://doi.org/10.12968/jowc.2014.23.11.570

Drosou A, Falabella A, Kirsner RS. Antiseptics on wounds: an area of controversy. Wounds. 2003; 149-66

Edwards-Jones V, Flanagan M. Wound infection. In: Flanagan M (Ed). Sussex: Wiley-Blackwell; 2013

Gardner SE, Frantz RA, Doebbeling B. The validity of the clinical signs and symptoms used to identify localized chronic wound infection. Wound Repair Regen. 2001; 9:(3)176-86

Hewish J. ‘I’ for infection: preventing local wound bed infection – a holistic approach to nursing assessment and management. Dermatological Nursing. 2014; 13:(4)10-15

Hübner N O, Siebert J, Kramer A. Octenidine dihydrochloride, a modern antiseptic for skin, mucous membranes and wounds. Skin Pharmacol Physiol. 2010; 23:(5)244-58 https://doi.org/10.1159/000314699

Hurlow J, Bowler PG. Clinical experience with wound biofilm and management: a case series. Ostomy Wound Manage. 2009; 55:(4)38-49

International Wound Infection Institute. Wound infection in clinical practice: principles of best practice. 2016. http://www.woundinfection-institute.com/wp-content/uploads/2017/03/IWII-Wound-infection-in-clinical-practice.pdf (accessed 8 July 2019)

Keast D, Swanson T. Ten top tips: managing surgical site infections. Wounds International. 2014; 5:(3)13-18 https://www.woundsinternational.com/download/resource/6866

Lenselink E, Andriessen A. A cohort study on the efficacy of a polyhexanidecontaining biocellulose dressing in the treatment of biofilms in wounds. J Wound Care. 2011; 20:(11)534-9 https://doi.org/10.12968/jowc.2011.20.11.534

Metcalf DG, Bowler PG, Hurlow J. A clinical algorithm for wound biofilm identification. J Wound Care. 2014; 23:(3)137-42 https://doi.org/10.12968/jowc.2014.23.3.137

Nakagami G, Schultz G, Gibon DJ Biofilm detection by wound blotting can predict slough development in pressure ulcers: a prospective observational study. Wound Repair Regen. 2017; 25:(1)131-8 https://doi.org/10.1111/wrr.12505

National Institute for Health and Care Excellence. Antimicrobial stewardship: systems and processes for antimicrobial medicine use. 2015. http://www.nice.org.uk/guidance/ng15 (accessed 8 July 2019)

National Institute for Clinical Excellence. Leg ulcer infection: antimicrobial prescribing guidance. 2019. https://www.nice.org.uk/guidance/GID-NG10133/documents/draft-guideline (accessed 15 July 2019)

NHS. Causes: sepsis. 2019. https://www.nhs.uk/conditions/sepsis/causes/ (accessed 15 July 2019)

Percival SL, Suleman L. Slough and biofilm: removal of barriers to wound healing by desloughing. J Wound Care. 2015; 24:(11)498-510 https://doi.org/10.12968/jowc.2015.24.11.498

Public Health England. Management of infection guidance for primary care for consultation and local adaptation. 2014. https://www.gov.uk/government/publications/managing-common-infections-guidance-for-primary-care (accessed 8 July 2019)

Schultz G, Sibbald RG, Falanga V Wound bed preparation: a systematic approach to wound management. Wound Repair Regen. 2003; 11:1-28

Sepsis Alliance. Definition of sepsis. 2019. https://www.sepsis.org/sepsis-basics/what-is-sepsis/ (accessed 15 July 2019)

Sibbald RG, Elliott JA. The role of Inadine in wound care: a consensus document. Int Wound J. 2016; 14:(2)316-21 https://doi.org/10.1111/iwj.12602

Siddiqui AR, Bernstein JM. Chronic wound infection: facts and controversies. Clinics in Dermatology. 2010; 28:(5)519-26 https://doi.org/10.1016/j.clindermatol.2010.03.009

Swanson T, Keast D, Cooper R Ten top tips: identification of wound infection in a chronic wound. Wounds International. 2015; 8:(2)19-21

Vanscheidt W, Harding K, Téot L, Siebert J. Effectiveness and tissue compatibility of a12-week treatment of chronic venous leg ulcers with an octenidinebased antiseptic – a randomized, double-blind controlled study. Int Wound J. 2012; 9:(3)316-323 https://doi.org/10.1111/j.1742-481X.2011.00886.x

Vermeulen H, Westerbos SJ, Ubbink DT. Benefit and harm of iodine in wound care: a systematic review. J Hosp Infect. 2010; 76:(3)191-9 https://doi.org/10.1016/j.jhin.2010.04.026

White RJ, Cutting KF. Wound biofilms – are they visible?. J Wound Care. 2012; 21:(3)140-1 https://doi.org/10.12968/jowc.2012.21.3.140

World Union of Wound Healing Societies. Wound Infection in Clinical Practice: An International consensus. 2008. https://www.woundsinternational.com/download/resource/6025 (accessed 19 July 2019)

Wolcott RD, Rhoads DD. A study of biofilm-based wound management in subjects with critical limb ischaemia. J Wound Care. 2008; 17:(4)145-55 https://doi.org/10.12968/jowc.2008.17.4.28835

Wounds UK. Best practice statement: making day-to-day management of biofilm simple. 2017. https://www.wounds-uk.com/resources/details/best-practice-statement-making-daytoday-management-biofilm-simple (accessed 8 July 2019)

Interventions in infected venous leg ulceration in clinical practice

02 August 2019
Volume 30 · Issue 8

Abstract

Annemarie Brown explores the vital role practice nurses play in caring for patients with infected venous leg ulcers. In particular, recognising signs and symptoms, management, and the threat of antimicrobial resistance will be discussed

This article aims to inform practice nurses of the management of infection in venous leg ulcers which they may encounter in clinical practice. It outlines the infection continuum, how to recognise the signs and symptoms of an increasing bacterial burden and how this can be effectively managed to prevent the patient developing a systemic infection. In view of Government policies to reduce the inappropriate use of systemic antibiotics, guidance on using topical antiseptics and antimicrobials is discussed, together with information on the various products available. The signs of sepsis are discussed to ensure that readers are familiar with this life-threatening condition.

Any breach of the skin, such as a wound, will cause bacteria to develop as a result of being open and exposed to the elements for a long time (Barrett, 2017). Venous leg ulcers, like all chronic wounds with a long healing time, are at risk of developing wound infection. Careful observation and a timely response to subtle signs can prevent a systemic wound infection developing. In order to achieve this, it is helpful for health professionals to be familiar with the continuum of wound infection and to be able to intervene appropriately before a systemic wound infection develops.

Contamination is when microbes (bacteria and fungi) are present, but at levels that are not causing any problems with the wound. No treatment is necessary but frequent observation and on-going reassessment is required (Edwards-Jones and Flanagan, 2013; International Wound Infection Institute (IWII), 2016).

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